Hypothetical breast cancer screening test:

The given table displays the results of the hypothetical Breast Cancer screening test

Results of a Hypothetical Screening Test for Breast Cancer Screening Test

Cancer confirmed

Cancer not confirmed

Total

Positive

133

 

982

 

1,115

Negative

46

 

63,649

 

63,695

Total

178

64,632

64,810

a) Determine the sensitivity of this test and explain what this means 

b) Determine the specificity of this test and explain what this means

c) Determine the positive predictive value and explain what this means

d) If the preclinical prevalence of breast cancer increased in the screened population would you expect the positive predictive value to increase, decrease or remain unaltered? Why?

e) If the sensitivity of this test improved within the screened population would you expect the positive predictive value to increase, decrease or remain unaltered? Why? 

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