Question: NMR spectroscopists often do experiments in D2O. The deuterium atoms in D2O can exchange for hydrogens in an organic molecule if and only if those hydrogens are exposed to solvent and are attached to polar atoms. These hydrogens are described as exchangeable; other hydrogens in the organic molecule are described as non-exchangeable. Which hydrogens in a deoxyribose moiety of a DNA nucleotide are exchangeable?