The genotype frequencies of a two allele polymorphism were measured from a sample of 200 individuals. The results were:
Genotype A/A A/B B/B
Frequencies 0.0 0.4 0.6
Does this represent a significant departure from the Hardy-Weinberg ratios? Further studies show that the absence of the A/A genotype is due to the lethal effect of the A allele when homozygous. Assuming that the measured gene frequencies are equilibrium values, what is the expected fitness of the B/B homozygote relative to the heterozygote?
