Q. Consider a transmembrane protein complex that forms a hydrophilic pore across the plasma membrane of a eukaryotic cell. The pore is made of five similar protein subunits, each of which contributes a membrane-spanning alpha-helix to form the pore. Each alpha helix has hydrophilic amino acid side chains on one side of the helix and hydrophobic amino acid side chains on the opposite side. Propose a possible arrangement of these five alpha helices in the membrane. Feel free to sketch this structure, but make sure you label everything clearly.
