Question: Assume you are a population geneticist, studying a particular disease which is inherited as an autosomal recessive trait. In the population you are studying, the incidence of the disease is 3%. you need to determine answers to the following questions:
- calculate the frequency of the normal allele and the disease allele in this population
- What percentage of your population are carriers for this disease?
- If this disease is fatal in childhood, what will be the frequency of the normal and disease allele in the parental generation (breeding adults)?
- If the disease is fatal in childhood, what will the incidence of the dease in the following generation be?